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Micotherapy TRD

Micotherapy TRD è un integratore che sfrutta la sinergia unica dei funghi Ganoderma lucidum e Agaricus blazei Murrill di origine biologica, con Fucus vesiculosus, Tirosina, Zinco, Selenio, CoQ10 e Vitamine B6, B9 e B12, appositamente formulato per effettuare una protezione della ghiandola tiroidea in caso di ipotiroidismi, funzionali o subclinici, anche di natura autoimmune


70 capsule

Mdo d'uso

1 capsula 3 volte al giorno, preferibilmente lontano dai pasti


Micotherapy TRD è un integratore alimentare studiato per migliorare la funzionalità tiroidea: i funghi Reishi e ABM aiutano a controllare l'asse dello stress, controllando l’eccesso di cortisolo e sostenendo il corretto equilibrio immunitario. Tirosina, Selenio, Iodio e vitamine del gruppo B favoriscono la corretta produzione di ormoni tiroidei, contribuendo alla protezione della tiroide da elevato stress ossidativo. Tra i principali sintomi di ipotiroidismo, sui quali Micotherapy TRD si rivela utile si riscontrano: astenia, debolezza, aumento di peso, ritenzione idrica, perdita di capelli/fragilità di unghie e capelli, secchezza cutanea, difficoltà di concentrazione e di memoria, sonnolenza, cefalea, alterazioni del ciclo mestruale, rallentamento motorio e verbale, alterazioni dell’alvo intestinale e ridotta funzionalità epatica

Effetti principali

Utile per favorire la corretta funzionalità tiroidea e la produzione degli ormoni tiroidei in caso di ipotiroidismo, anche di natura autoimmune

Informazioni nutrizionali


Per dosaggio giornaliero

Agaricus blazei estr. secco 750 mg
Apporto in polisaccaridi 187,5 mg
Reishi estr. secco 750 mg
L-tirosina 300 mg
Fucus estr. secco 225 mg
Apporto in iodio 225 mcg
CoQ10 150 mg
Zinco 15 mg
Vitamina B6 (piridossina) 9,5 mg
Acido folico (Vit B9) 400 mcg
Selenio 83 mcg
Vitamina B12 (cianocobalamina) 33 mcg
Reperibilità prodotto

Codice parafarmaco: A973731108

Inserito nel registro degli integratori n°:


• Zimmermann MB (2011). Role of iodine in human growth and development. Semin Cell Dev Biol 22: 645-65.

• Caldwell KL, et al., (2008) Iodine status of the US population, National Health and Nutrition Examination Survey 2003-2004. Thyroid, 18:1207-1214.

• Pearce, et al., (2017) Environmental Iodine Uptake Inhibitors. Iodine Deficiency Disorders and Their Elimination. Springer International Publishing, 141-153.

• Ferrari, Silvia Martina, et al. (2017). Environmental issues in thyroid diseases. Frontiers in endocrinology 8 (2017).

• Goyal I. et al., Hypothyroidism and goiter in a young male with suspected dietary iodine deficiency followed by thyrotoxicosis after iodine supplementation. AACE Clin Case Rep. 2020 Sep 26;6(1):e19-e22. 

• Wol J, Chaiko IL (1948) Plasma inorganic iodide as a homeostatic regulator of thyroid function. J Biol Chem 174: 555-564.

• Patey-Pirra S, et al., (2014) Benefits and risks of iodine supplementation during pregnancy: a review of observational and experimental studiesbin mild-to-moderate iodine deficiency area. Rev Epidemiol Sante Publique 62: 65-74.

• Nazeri P, et al., (2015) Iodine nutrition status in lactating mothers residing in countries with mandatory and voluntary iodine fortification programs: An updated systematic review. Thyroid 25: 611-620.

• Taylor PN, et al., (2014) Therapy of endocrine disease: impact of iodine supplementation in mild-to- moderate iodine de_ciency: systematic review and meta-analysis. Eur J Endocrinol 170:1-15. 

• Guess K, Malek L, Anderson, A, Makrides, M, Zhou SJ (2016) Knowledge and practices regarding iodine supplementation: A national survey of healthcare providers. Women Birth 30: e56-e60.

• Zava TT, Zava DT (2011). Assessment of Japanese iodine intake based on seaweed consumption in Japan: a literature-based analysis. yroid research 4: 1-1.

• Vanderpump, Mark P (2017). Epidemiology of iodine deficiency. Minerva medica 108: 116-123. 

• Kim, Hye Jeong, et al. (2017) Strong association of relatively low and extremely excessive iodine intakes with thyroid cancer in an iodine-replete area. European journal of nutrition 56.3: 965-971.

• Malamos, B., et al. The serum tyrosine level as an index of thyroid function. Journal of Endocrinology 35.3 (1966): 223-228.

• W. Khalig et al., Reductions in tyrosine levels are associated with thyroid hormone and catecholamine disturbances in sepsis. Intensive Care Med Exp. 2015 Dec; 3(Suppl 1): A686.

• Schomburg L. Selenium, selenoproteins, and the thyroid gland: interactions in health and disease. Nat Rev Endocrinol. 2011;8(3):160-71.

• Triggiani V, Tafaro E, Giagulli VA, et al. Role of iodine, selenium and other micronutrients in thyroid function and disorders. Endocr Metab Immune Disord Drug Targets. 2009 Sep;9(3):277-94. Review.

• Leoni SG. et al., Selenium increases thyroid-stimulating hormone-induced sodium/iodide symporter expression through thioredoxin/apurinic/apyrimidinic endonuclease 1-dependent regulation of paired box 8 binding activity, Antioxid. Redox Signal. 24 (2016) 855–866.

• 34. Kohrle, J., et al. “Selenium, the thyroid, and the endocrine system.” Endocrine reviews 26.7 (2005): 944-984.

• H. Kamada, et al., Effects of selenium supplementation on plasma progesterone concentrations in pregnant heifers, Anim. Sci. J. 85 (2014) 241–246

• A. Singh, et al., Biochemical indices of selected trace minerals in men: effect of stress, Am. J. Clin. Nutr. 53 (1991) 126–131.

• Gärtner, Roland, et al. “Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.” The Journal of Clinical Endocrinology & Metabolism 87.4 (2002): 1687-1691.

• Marinò M., et al. “Selenium in the Treatment of Thyroid Diseases.” European Thyroid Journal 6.2 (2017): 113-114. 

• Nordio, M. “A novel treatment for subclinical hyperthyroidism: a pilot study on the beneficial effects of l-carnitine and selenium.” European Review for Medical and Pharmacological Sciences 21 (2017): 2268-2273.

• G. Lenaz et al., Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject, Antioxid. Redox Signal 12 (2010) 961–1008.

• Moncayo, Roy, and Helga Moncayo. Applying a systems approach to thyroid physiology: Looking at the whole with a mitochondrial perspective instead of judging single

• TSH values or why we should know more about mitochondria to understand metabolism. BBA clinical (2017).

• A. Ben-Meir, et al., Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging, Aging Cell 14 (2015) 887–895.

• S.G. Leoni, et al., Regulation of thyroid oxidative state by thioredoxin reductase has a crucial role in thyroid responses to iodide excess, Mol. Endocrinol. 25 (2011) 1924–1935.

• P. Rani, K. Lalitha, Evidence for altered structure and impaired mitochondrial electron transport function in selenium deficiency, Biol. Trace Elem. Res. 51 (1996) 225–234

• Hartoma, R., Effect of zinc on some biochemical indices of metabolism. Annals of Nutrition and Metabolism 23.4 (1979): 294-300.

• Betsy A., et al., Zinc deficiency associated with hypothyroidism: an overlooked cause of severe alopecia, Int. J. Trichol. 5 (2013) 40–42.

• Alvarez-Salas E. et al., Mediobasal hypothalamic and adenohypophyseal TRH- degrading enzyme (PPII) is down-regulated by zinc deficiency, Int. J. Dev. Neurosci. 46 (2015) 115–124.

• Pathak R and Pathak A. Effectiveness of Zinc Supplementation on Lithium-Induced Alterations in Thyroid Functions. Biol Trace Elem Res. 2020 Aug 26.

• Ihnatowicz P, Drywień M, Wątor P, Wojsiat J. et al., The importance of nutritional factors and dietary management of Hashimoto’s thyroiditis. .Ann Agric Environ Med. 2020 Jun 19;27(2):184-193. 

• Mahmoodianfard S. et al., Effects of zinc and selenium supplementation on thyroid function in overweight and obese hypothyroid female patients: a randomized double-blind controlled trial. Journal of the American College of Nutrition 34.5 (2015): 391-399.

• Ihnatowicz P. et al., The importance of nutritional factors and dietary management of Hashimoto’s thyroiditis. Ann Agric Environ Med. 2020 Jun 19;27(2):184-193

• Nechyporuk Vet al., The impact of B vitamins on the functioning of methylation cycle in the liver and the kidneys of hyper- and hypothyroid rats. Pol Merkur Lekarski. 2020 Feb 26;48(283):55-59.

• Priyadarshini R., The Prevalence of Vitamin B12 Defi ciency in Patients with Hypothyroidism. J Assoc Physicians India. 2020 Jan;68(1):44.

• Apeland T. Thyroid function during B-vitamin supplementation of patients on antiepileptic drugs.Clin Biochem. 2006 Mar;39(3):282-6. 

• Diekman, M. J. M., et al. “Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism.” Clinical endocrinology 54.2 (2001): 197-204.

• Lien, E. A., et al. “Plasma total homocysteine levels during short-term iatrogenic hypothyroidism.” The Journal of Clinical Endocrinology & Metabolism 85.3 (2000): 1049-1053.

• Patocka J. Anti-inflammatory triterpenoids from mysterious mushroom Ganoderma lucidum and their potential possibility in modern medicine. Acta Medica 42.4 (1999): 123-125.

• Sheena, N. et al., Anti-inflammatory and anti-nociceptive activities of Ganoderma lucidum occurring in South India. Pharmaceutical biology 41.4 (2003): 301-304.

• Paterson, R. Russell M. Ganoderma–a therapeutic fungal biofactory. Phytochemistry 67.18 (2006): 1985-2001.

• Toshihiro A. et al., Anti-Inflammatory and Anti-Tumor Promoting Effects of Triterpene Acids and Sterols from the Fungus Ganoderma lucidum.” Chemistry & biodiversity 4.2 (2007): 224-231.

• Dudhgaonkar, Shailesh, Anita Thyagarajan, and Daniel Sliva. “Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum.” International immunopharmacology 9.11 (2009): 1272-1280.

• Joseph S. et al. Antitumor and anti-inflammatory activities of polysaccharides isolated from Ganoderma lucidum. Acta pharmaceutica 61.3 (2011): 335-342.

• Yoon, Hyun-Min, et al. Ganoderma lucidum ethanol extract inhibits the inflammatory response by suppressing the NF-kB and toll-like receptor pathways in lipopolysaccharide-stimulated BV2 microglial cells.” Experimental and therapeutic medicine 5.3 (2013): 957-963.

• Keith R. The novel antioxidant ergothioneine found in dietary mushrooms inhibits monocyte binding to human aortic endothelial cells.” The FASEB Journal 22.1

• Sit, A. S. M., et al. “Potential beneficial effect of ergothioneine in protecting endothelial dysfunction.” Basic & Clinical Pharmacology & Toxicology (2010).

Linee prodotti


Micotherapy è la linea di prodotti AVD Reform a base di funghi medicinali provenienti da coltivazioni biologiche certificate.